Necator americanus in inbred mice: a re-evaluation of primary infection kinetics
نویسندگان
چکیده
منابع مشابه
The course of primary infection with Necator americanus in syngeneic mice.
WELLS C. and BEHNKE .I. M. 1988. The course of primary infection with Necutoramericanus in syngeneic mice. Internationul Journul for Purasitology 18: 41-5 1. A panel of syngeneic mouse strains was compared for susceptibility to infection with a hamster adapted strain of N. americunus. Lung worm burdens were compared 4-5 days after percutaneous exposure to 190-375 larvae. SJL and DBA/l were most...
متن کاملStage-specific immune responses in human Necator americanus infection
We describe how hookworms interact with their human hosts by comparing lymphocyte phenotyping, proliferative responses, and cytokine and chemokine secretion patterns in adults who are either mono-infected with Necator americanus or egg-negative controls resident in an area of high transmission in Brazil. Cellular immune responses against crude hookworm antigen extracts from different developmen...
متن کاملCross-reactivity between Necator americanus and Schistosoma mansoni in mice.
Poly-parasitism is common in endemic communities and reactivity of sera from hookworm-infected patients against schistosomular antigens has been reported. Protective cross-immunity between N. americanus and S. mansoni was investigated in NIH and BALB/c mice. Protective resistance to homologous challenge with both parasites was confirmed in this model, however, functional immunity to heterologou...
متن کاملThe physicochemical fingerprint of Necator americanus
Necator americanus, a haematophagous hookworm parasite, infects ~10% of the world's population and is considered to be a significant public health risk. Its lifecycle has distinct stages, permitting its successful transit from the skin via the lungs (L3) to the intestinal tract (L4 maturing to adult). It has been hypothesised that the L3 larval sheath, which is shed during percutaneous infectio...
متن کاملSystems metabolic effects of a necator americanus infection in Syrian hamster.
Hookworms (Ancylostoma duodenale and Necator americanus) are blood-feeding intestinal nematodes that infect approximately 700 million people worldwide. To further our understanding of the systems metabolic response of the mammalian host to hookworm infection, we employed a metabolic profiling strategy involving the combination of (1)H NMR spectroscopic analysis of urine and serum and multivaria...
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ژورنال
عنوان ژورنال: Parasitology
سال: 1993
ISSN: 0031-1820,1469-8161
DOI: 10.1017/s0031182000067780